Table 4 Distribution of RAS gene polymorphisms (dominant and recessive model) in patient and control subjects.
SNPs Model TEST Case (
) Control (
) OR 95% CI
valueAGT M235TMM + MT versus TT DOM 94/117 108/103 0.766 0.513–1.144 0.173 MM versus MT + TT REC 13/198 30/181 0.396 0.184–0.813
Male MM + MT versus TT DOM 52/57 64/66 0.941 0.547–1.616 0.814 MM versus MT + TT REC 9/100 16/114 0.641 0.239–1.624 0.308 Female MM + MT versus TT DOM 42/60 44/37 0.589 0.313–1.106 0.077 MM versus MT + TT REC 04/98 14/67 0.062 0.015–0.185 0.000 ACE I/DII + ID versus DD DOM 128/83 144/67 0.718 0.471–1.092 0.104 II versus ID + DD REC 40/171 51/160 0.734 0.447–1.201 0.193 Male II + ID versus DD DOM 59/50 97/33 0.401 0.224–0 .718
II versus ID + DD REC 19/90 30/100 0.704 0.349–1.397 0.282 Female II + ID versus DD DOM 69/33 47/34 1.513 0.789–2.898 0.180 II versus ID + DD REC 21/81 21/60 0.741 0.350–1.569 0.394 ACE G2350AAA + AG versus GG DOM 61/150 58/153 1.073 0.686–1.677 0.746 AA versus AG + GG REC 12/199 11/200 1.096 0.432–2.813 0.830 Male AA + AG versus GG DOM 31/78 29/101 1.384 0.738–2.596 0.276 AA versus AG + GG REC 7/102 6/124 1.418 0.394–0.273 0.540 Female AA + AG versus GG DOM 30/72 29/52 0.747 0.383–1.462 0.358 AA versus AG + GG REC 05/97 05/76 0.784 0.174–0.542 0.707 A1166C CC + CT versus TT DOM 123/88 126/85 0.943 0.628–1.416 0.767 CC versus CT + TT REC 39/172 43/168 0.886 0.530–1.477 0.623 Male CC + CA versus AA DOM 68/41 77/53 1.142 0.656–1.992 0.619 CC versus CA + AA REC 20/89 25/105 0.944 0.464–1.903 0.862 Female CC + CA versus AA DOM 55/47 49/32 0.764 0.405–1.439 0.373 CC versus CA + AA REC 19/83 18/63 0.801 0.365–1.767 0.548
DOM: dominant model; REC: recessive model;
: sample size; OR: odds ratio; CI: confidence interval;
: statically significant.
