BioMed Research International / 2014 / Article / Tab 4

Research Article

Gender Specific Association of RAS Gene Polymorphism with Essential Hypertension: A Case-Control Study

Table 4

Distribution of RAS gene polymorphisms (dominant and recessive model) in patient and control subjects.

SNPsModelTESTCase ( )Control ( )OR95% CI value

AGT M235TMM + MT versus TTDOM94/117108/1030.7660.513–1.1440.173
MM versus MT + TTREC13/19830/1810.3960.184–0.813
 MaleMM + MT versus TTDOM52/5764/660.9410.547–1.6160.814
MM versus MT + TTREC9/10016/1140.6410.239–1.6240.308
 FemaleMM + MT versus TTDOM42/6044/370.5890.313–1.1060.077
MM versus MT + TTREC04/9814/670.0620.015–0.1850.000

ACE I/DII + ID versus DDDOM128/83144/670.7180.471–1.0920.104
II versus ID + DDREC40/17151/1600.7340.447–1.2010.193
 MaleII + ID versus DDDOM59/5097/330.4010.224–0 .718
II versus ID + DDREC19/9030/1000.7040.349–1.3970.282
 FemaleII + ID versus DDDOM69/3347/341.5130.789–2.8980.180
II versus ID + DDREC21/8121/600.7410.350–1.5690.394

ACE G2350AAA + AG versus GGDOM61/15058/1531.0730.686–1.6770.746
AA versus AG + GGREC12/19911/2001.0960.432–2.8130.830
 MaleAA + AG versus GGDOM31/7829/1011.3840.738–2.5960.276
AA versus AG + GGREC7/1026/1241.4180.394–0.2730.540
 FemaleAA + AG versus GGDOM30/7229/520.7470.383–1.4620.358
AA versus AG + GGREC05/9705/760.7840.174–0.5420.707

A1166CCC + CT versus TTDOM123/88126/850.9430.628–1.4160.767
CC versus CT + TTREC39/17243/1680.8860.530–1.4770.623
 MaleCC + CA versus AADOM68/4177/531.1420.656–1.9920.619
CC versus CA + AAREC20/8925/1050.9440.464–1.9030.862
 FemaleCC + CA versus AADOM55/4749/320.7640.405–1.4390.373
CC versus CA + AAREC19/8318/630.8010.365–1.7670.548

DOM: dominant model; REC: recessive model; : sample size; OR: odds ratio; CI: confidence interval; : statically significant.

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