Research Article

The Gene-Gene Interaction of INSIG-SCAP-SREBP Pathway on the Risk of Obesity in Chinese Children

Table 3

Frequency differences of 9 high-risk genotype combinations of INSIG-SCAP-SREBP pathway between obese and nonobese children.

rs9308672/rs12487736/rs1883205Obese ( )Nonobese ( )Percentage ratio
NumberPercentageNumberPercentage(obese/nonobese)

CC/GG/CC152.16 231.75 1.23
CC/AG/CT446.35 634.81 1.32
CC/GG/TT81.15 100.76 1.51
CT/AA/CC395.63 423.20 1.76
CT/AG/CC557.94 906.86 1.16
CT/GG/CC375.34 453.43 1.56
CT/AG/TT375.34 554.20 1.27
TT/GG/CT375.34 372.82 1.89
TT/GG/TT131.88 100.76 2.46

Total 28541.13 37528.60 1.44