Research Article
The Gene-Gene Interaction of INSIG-SCAP-SREBP Pathway on the Risk of Obesity in Chinese Children
Table 3
Frequency differences of 9 high-risk genotype combinations of INSIG-SCAP-SREBP pathway between obese and nonobese children.
| rs9308672/rs12487736/rs1883205 | Obese () | Nonobese () | Percentage ratio | Number | Percentage | Number | Percentage | (obese/nonobese) |
| CC/GG/CC | 15 | 2.16 | 23 | 1.75 | 1.23 | CC/AG/CT | 44 | 6.35 | 63 | 4.81 | 1.32 | CC/GG/TT | 8 | 1.15 | 10 | 0.76 | 1.51 | CT/AA/CC | 39 | 5.63 | 42 | 3.20 | 1.76 | CT/AG/CC | 55 | 7.94 | 90 | 6.86 | 1.16 | CT/GG/CC | 37 | 5.34 | 45 | 3.43 | 1.56 | CT/AG/TT | 37 | 5.34 | 55 | 4.20 | 1.27 | TT/GG/CT | 37 | 5.34 | 37 | 2.82 | 1.89 | TT/GG/TT | 13 | 1.88 | 10 | 0.76 | 2.46 |
| Total | 285 | 41.13 | 375 | 28.60 | 1.44 |
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