Therapeutic Efficacy of Vitamin E -Tocotrienol in Collagen-Induced Rat Model of Arthritis
Figure 3
Histopathological analysis of joint morphology (H&E-200x). (a) Photomicrograph of arthritis group, showing synovial fibrosis (black arrow) and inflammatory infiltrate forming a pannus (red circle), (b) photomicrograph of arthritis + delta-tocotrienol, showing a significant reduction in synovial hyperplasia and inflammation (black arrow) and healthy joint space (black double arrow head), (c) photomicrograph of arthritis with glucosamine group, showing angiogenesis in the form of proliferating blood vessels (blue circle) and surrounding synovial healing scar tissue (black double arrow head), and (d) photomicrograph of control group, showing healthy normal joint space (double arrow head) with no inflammation or hyperplasia.
