Evaluation of Anticonvulsant, Sedative, Anxiolytic, and Phytochemical Profile of the Methanol Extract from the Aerial Parts of Swertia corymbosa (Griseb.) Wight ex C.B. Clarke

Table 4

Effect of methanol extract of Swertia corymbosa (SCMeOH) on locomotor activity (actophotometer) in rats.

Treatment (mg/kg)	Locomotor activity in 10 min		% change in activity
	Before	After 60 minutes
Control	294.5 ± 16.69	281.23 ± 11.43
Diazepam (2 mg/kg)	289.56 ± 6.23	145.96 ± 3.25	49.59**
SCMeOH 125	287.51 ± 9.17	180.12 ± 2.34	37.35
SCMeOH 250	299.50 ± 10.62	162.60 ± 2.49	45.70*
SCMeOH 500	298.44 ± 12.20	133.16 ± 3.19	55.38**

Control (vehicle)—distilled water.
The data represent the mean ± SD (𝑛=6). *𝑃<0.01, **𝑃<0.001 significantly different compared to normal control.