Evaluation of Anticonvulsant, Sedative, Anxiolytic, and Phytochemical Profile of the Methanol Extract from the Aerial Parts of Swertia corymbosa (Griseb.) Wight ex C.B. Clarke

Table 5

Effect of methanol extract of Swertia corymbosa (SCMeOH) on motor (rotarod) coordination in mice.

	Experimental mean time (10 min) (s)		% of muscle griping
	Before	After 60 minutes
Control	69.16 ± 2.18	67.00 ± 2.89
Diazepam (2 mg/kg)	64.73 ± 5.82	13.30 ± 7.42	—
SCMeOH 125	70.23 ± 3.12	127.19 ± 4.32	40.78
SCMeOH 250	65.78 ± 2.89	199.56 ± 2.43	67.03*
SCMeOH 500	70.12 ± 1.22	276.35 ± 7.58	74.62**

Control (vehicle)—distilled water.
The data represent the mean ± SD (𝑛=6). *𝑃<0.01, **𝑃<0.001 significantly different compared to normal control and diazepam.