Molecular and Cellular Basis of Autosomal Recessive Primary Microcephaly

Table 1

Gene table: autosomal recessive primary microcephaly (MCPH).

Gene	Locus	Gene product	References (gene and/or locus)	OMIM
MCPH1 MICROCEPHALIN	MCPH1	MICROCEPHALIN	[40]	607117
WDR62 (WD repeat-containing protein 62)	MCPH2	WDR62	[169]	613583
CDK5RAP2 (CDK5 regulatory subunit-associated protein 2)	MCPH3	CDK5RAP2	[170]	608201
CASC5 (cancer susceptibility candidate 5)	MCPH4	CASC5	[171]	609173
ASPM (abnormal spindle-like microcephaly-associated protein)	MCPH5	ASPM	[172]	605481
CENPJ (centromere protein J)	MCPH6	CENPJ	[15]	609279
STIL (SCL/TAL1-interrupting locus)	MCPH7	STIL	[25]	181590
CEP135 (centrosomal protein of 135 kDa)	MCPH8	CEP135	[26]	611423
CEP152 (centrosomal protein of 152 kDa)	MCPH9	CEP152	[27]	613529
ZNF335 (zinc finger protein 335)	MCPH10	ZNF335	[156]	610827
PHC1 (polyhomeotic-like protein 1)	MCPH11	PHC1	[157]	602978
CDK6 (cyclin-dependent kinase 6)		CDK6	[29]	603368