Synergistic Effects of Toxic Elements on Heat Shock Proteins

<table>The concentration-response curve of<i> Neomysis integer</i> for a mixture of six metals at different salinities (5, 10, 15, and 25<svg height="11.75" id="M6" style="vertical-align:-0.23825pt" version="1.1" viewbox="0 0 18.174999 11.75" width="18.174999" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,-0,0,-.017,.062,11.15)"><path d="M586 629l-403 -661l-31 23l402 661zM192 635q47 0 80.5 -28.5t47.5 -67.5t14 -81q0 -67 -37 -122t-106 -55q-68 0 -105 54.5t-37 121.5q0 69 37 123.5t106 54.5zM192 606q-28 0 -44.5 -28t-21 -57.5t-4.5 -61.5q0 -22 3 -45t10 -48t22 -41t36 -16t36 16t21 42t8.5 47.5
t2.5 43.5q0 148 -69 148zM554 343q68 0 104.5 -55t36.5 -123q0 -67 -37 -122t-105 -55q-69 0 -106 55t-37 122q0 68 37 123t107 55zM876 343q68 0 105 -55t37 -123q0 -67 -37 -122t-106 -55q-68 0 -105 55t-37 122q0 42 14.5 81.5t48 68t80.5 28.5zM553 314q-21 0 -36 -15.5
t-22 -40.5t-9.5 -47t-2.5 -45q0 -22 3 -44.5t9.5 -48t22 -41t36.5 -15.5t35.5 16t21 41.5t9 47t2.5 43.5q0 23 -2.5 45t-9 47.5t-21.5 41t-36 15.5zM875 314q-21 0 -35.5 -15.5t-21.5 -40.5t-9.5 -47t-2.5 -45q0 -22 2.5 -44.5t9.5 -48t22 -41t36 -15.5t36 16t21.5 41.5
t9 47t2.5 43.5q0 23 -2.5 44.5t-9 47.5t-21.5 41.5t-37 15.5z" id="x2030"></path></g>
</svg>). The toxicity decreases with increasing salinity and higher salinities above 25<svg height="11.75" id="M7" style="vertical-align:-0.23825pt" version="1.1" viewbox="0 0 18.174999 11.75" width="18.174999" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,-0,0,-.017,.062,11.15)"><path d="M586 629l-403 -661l-31 23l402 661zM192 635q47 0 80.5 -28.5t47.5 -67.5t14 -81q0 -67 -37 -122t-106 -55q-68 0 -105 54.5t-37 121.5q0 69 37 123.5t106 54.5zM192 606q-28 0 -44.5 -28t-21 -57.5t-4.5 -61.5q0 -22 3 -45t10 -48t22 -41t36 -16t36 16t21 42t8.5 47.5
t2.5 43.5q0 148 -69 148zM554 343q68 0 104.5 -55t36.5 -123q0 -67 -37 -122t-105 -55q-69 0 -106 55t-37 122q0 68 37 123t107 55zM876 343q68 0 105 -55t37 -123q0 -67 -37 -122t-106 -55q-68 0 -105 55t-37 122q0 42 14.5 81.5t48 68t80.5 28.5zM553 314q-21 0 -36 -15.5
t-22 -40.5t-9.5 -47t-2.5 -45q0 -22 3 -44.5t9.5 -48t22 -41t36.5 -15.5t35.5 16t21 41.5t9 47t2.5 43.5q0 23 -2.5 45t-9 47.5t-21.5 41t-36 15.5zM875 314q-21 0 -35.5 -15.5t-21.5 -40.5t-9.5 -47t-2.5 -45q0 -22 2.5 -44.5t9.5 -48t22 -41t36 -15.5t36 16t21.5 41.5
t9 47t2.5 43.5q0 23 -2.5 44.5t-9 47.5t-21.5 41.5t-37 15.5z" id="x2030"></path></g>
</svg> had no further influence on the 96 h LC50 of the mixture of six metals (Hg, /Cd, /Cu, /Zn, Ni, /Pb) which is situated at a value between 4.4 and 4.6 T.U [<a href="/journals/bmri/2014/564136/#B115">104</a>].</table>

BioMed Research International

Synergistic Effects of Toxic Elements on Heat Shock Proteins

Figure 7