Research Article
The Influence of Ionizing Radiation, Temperature, and Light on Eplerenone in the Solid State
Table 2
Degradation products of eplerenone [
7,
8].
| Stress conditions and duration | Degradation of eplerenone | Molecular formula | Molecular weight [Da] | Reference |
| 0.5 mol/L NaOH, 1 h, 25°C | 20.3 | C24H34O8 |
450.52 | [7] |
| 1 mol/lL NaOH, 2 h, 100°C | 93.0 | C24H32O7 | 432.51 | [8] |
| 1 mol/lL HCl, 2 h, 100°C | 90.0 | C23H32O5 | 388.50 | [8] | C23H28O6 | 400.46 | [8] | C22H32O2 | 328.49 | [8] |
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