The Influence of Ionizing Radiation, Temperature, and Light on Eplerenone in the Solid State
Table 5
Results of DSC analysis. The values in parentheses are standard deviation.
Conditions
Temperature [°C]
Difference [°C]
Nondegraded
234.5 (3)
248.5 (0)
253.5 (3)
—
—
—
6 mln lux h
232.6 (0)
248.3 (3)
253.2 (0)
90°C RH 0%
232.3 (6)
248.5 (0)
253.7 (3)
60°C RH 76.4%
231.7 (3)
248.2 (7)
253.6 (7)
25 kGy
227.6 (7)
246.1 (3)
249.8 (3)
50 kGy
227.3 (3)
245.7 (0)
249.3 (7)
100 kGy
226.4 (3)
244.1 (3)
247.8 (3)
200 kGy
226.7 (3)
242.0 (7)
246.5 (0)
400 kGy
227.5 (0)
239.6 (3)
242.5 (7)
: melting peak onset for nondegraded eplerenone. : melting peak maximum for nondegraded eplerenone. : melting peak endset temperature for nondegraded eplerenone.