Antidiabetic Activity of Acacia tortilis (Forsk.) Hayne ssp. raddiana Polysaccharide on Streptozotocin-Nicotinamide Induced Diabetic Rats

Table 2

Effect of AEATP on pancreatic insulin content (ng/mg pancreas) in type-2 diabetic Wistar rats.

Pancreatic insulin content (ng/mg pancreas)	Control	Diabetic control	Glimepiride treated	250 mg/kg of AEATP	500 mg/kg of AEATP	1000 mg/kg of AEATP
Basal	106.6 ± 3.35	101.9 ± 2.62	102.3 ± 3.66	101.9 ± 5.75	97.8 ± 5.99	100.9 ± 5.81
28th day	103.9 ± 5.24	56.0 ± 2.81^a#	99.9 ± 2.22^b#	67.0 ± 2.98^b‡	77.33 ± 5.68^b#, c#	92.46±3.14^b#,c#,d†

Each group (𝑛=6) represents mean ± standard error of means. Data was analyzed by using one-way ANOVA followed by Tukey’s multiple test; a control, b diabetic control, c 250 mg/kg of AEATP, d 500 mg/kg of AEATP. ^∗𝑃<0.0001, ^#𝑃<0.001, ^†𝑃<0.01, ^‡𝑃<0.05.