Research Article

Significance of Lewis Phenotyping Using Saliva and Gastric Tissue: Comparison with the Lewis Phenotype Inferred from Lewis and Secretor Genotypes

Table 3

Comparison between various Lewis phenotypes and the Lewis phenotype predicted from Lewis and Secretor genotypes.

le/le and −/− Le/− and se/se Le/− and Se/−
le/le le/le le/le Le/Le Le/le Le/Le Le/Le Le/le Le/le
Se/Se Se/se se/se se/se se/se Se/Se Se/se Se/Se Se/se
Le(a−b−)Le(a+b−)Le(a−b+)

Lewis phenotype in saliva*
Le(a−b−)0410000005
Le(a+b−)0003126000057
Le(a−b+)00000378165147
Le(a+b+)0000000000
Lewis phenotype on erythrocytes
Le(a−b−)031350311026
Le(a+b−)0002719150254
Le(a−b+)01011270053128
Le(a+b+)0000100001
Lewis phenotype in gastric mucosa**
Le(a−b−)011010311017
Le(a+b−)00064030114
Le(a−b+)0301114404595
Le(a+b+)00024202280983

The saliva Lewis phenotype through the hemagglutination inhibition test was consistent with the Lewis phenotype inferred from Lewis and Secretor genotypes.
The Lewis phenotype in gastric mucosa by immunohistochemistry was not predicted from Lewis and Secretor genotypes.