Conversion to Sirolimus Ameliorates Cyclosporine-Induced Nephropathy in the Rat: Focus on Serum, Urine, Gene, and Protein Renal Expression Biomarkers

Figure 4

Serum and urine NGAL correlation as kidney marker of toxicity. Urine (a), serum NGAL (b), and clearance (c) at week 9. Values are mean ± SEM. Correlation and 𝑃 value of urine and serum NGAL are shown in (d). ^∗𝑃<0.05, ^∗∗𝑃<0.01, and ^∗∗∗𝑃<0.001 versus the control group; ^#𝑃<0.05 versus cyclosporin A.

(a)

(b)

(c)

(d)