Conversion to Sirolimus Ameliorates Cyclosporine-Induced Nephropathy in the Rat: Focus on Serum, Urine, Gene, and Protein Renal Expression Biomarkers

Figure 7

Kidney protein expression by immunohistochemistry. CTGF (a), KIM-1 (b), mTOR (c), and NF-κB₁ (d). Each figure is representative of the groups at week 3 (control, cyclosporin A, and sirolimus) and 4 groups at week 9 (control, cyclosporin A, sirolimus, and conversion). CTGF, connective tissue growth factor; KIM-1, kidney injury molecule-1; mTOR, mammalian target of rapamycin; NF-κB₁, nuclear factor kappa beta-1.

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