PTEN Mediates the Antioxidant Effect of Resveratrol at Nutritionally Relevant Concentrations
Figure 5
Resveratrol diminishes peroxide levels in MCF-7 cells, and this effect is mediated by the PTEN/Akt signaling pathway. MCF-7 cells were treated with resveratrol (1 nM) alone, potassium bisperoxo (bipyridine) oxovanadate (V) as a PTEN inhibitor alone (20 nM), or both together. Data are expressed as means + SD for 4–8 different experiments; versus control.
