Epigenetic Silencing of CXCR4 Promotes Loss of Cell Adhesion in Cervical Cancer
Figure 1
Expression of CXCR4. (a) Semiquantitative reverse transcriptase PCR in normal cervix and tumor biopsy samples. Upper panel is CXCR4 and lower panel is β-Actin. (b) Immunoblotting with the cell lysate of normal cervix and tumor biopsy. (c) Box plot showing significant downregulation of CXCR4 in primary tumor (). (d) Histogram showing the result of immunoblotting in normal cervix and tumor biopsy. (e) Immunohistochemistry showing expression of CXCR4 in normal squamous epithelial cells. (f) Immunohistochemistry showing expression of CXCR4 in tumor biopsy sample. value ≤ 0.05. N = normal cervix and T = tumor biopsy.
