MicroRNAs 146a and 147b Biomarkers for Colorectal Tumor’s Localization

Table 2

Relationship between clinicopathological features and miRs expression in colon cancer tissue.

	Parameters
	𝑁=25	𝑃 value
MicroRNAs		miR146a	miR147b	miR135a	miR21	miR155
Gender
Male	17 (68%)	0.67	0.27	0.60	0.70	0.31
Female	8 (32%)
Tumor location
Right colon	11 (44%)	0.012	0.04	0.73	0.81	0.74
Left colon	14 (56%)
Tumor architecture
UIB*	13 (52%)	0.85	0.28	0.43	0.33	0.87
UI/U/B*	12 (48%)
Tumor differentiation
Low/moderate	6 (24%)	0.45	0.33	0.11	0.84	0.48
High	19 (76%)
Tumor histology
Nonmucinous carcinoma	21 (84%)	0.25	0.42	0.10	0.18	0.23
Mucinous carcinoma	4 (16%)
Lymph node
Absent	11 (44%)	0.95	0.85	0.88	0.66	0.51
Present	14 (56%)
TNM stage
I-II	10 (40%)	0.77	0.45	0.95	0.58	0.90
III-IV	15 (60%)

∗UIB: ulcerative infiltrative tumor budding; UI: ulcerative infiltrative tumor; U: ulcerative tumor; B: budding tumor.