Exploring Population Pharmacokinetic Modeling with Resampling Visualization

Figure 1

Multiple simulated data sets for resampling statistics. In the first simulation data set (sim1), when the subject is absent from the simulation, no parameter is estimated, so a missing value (NA) is generated. One of these tables is generated for each parameter (CL, V, and Ke). We can consider this to be a multivariate data set, which we will use to examine the influence of each subject and assess the variability in the parameter estimates.