Time-Intensity Curve Parameters in Rectal Cancer Measured Using Endorectal Ultrasonography with Sterile Coupling Gels Filling the Rectum: Correlations with Tumor Angiogenesis and Clinicopathological Features

Table 2

Correlations of CEUS time-intensity curve parameters with histologic grade and TNM stage.

CEUS parameter	Histologic grade		T stage		N stage		Metastasis
	Correlation coefficient	𝑃	Correlation coefficient	𝑃	Correlation coefficient	𝑃	Correlation coefficient	𝑃
Arrival time, s	0.104	0.287	0.037	0.696	−0.058	0.554	0.022	0.830
Time to peak enhancement, s	0.085	0.332	0.085	0.373	−0.021	0.829	0.058	0.569
Wash-in time, s	0.001	0.995	0.073	0.441	−0.024	0.804	0.018	0.859
Enhanced intensity, dB	−0.264	0.007	−0.158	0.096	−0.026	0.789	−0.018	0.859
Ascending slope	−0.116	0.232	−0.143	0.131	−0.008	0.934	−0.001	0.993

CEUS: contrast enhanced ultrasound.
Statistical method: bivariate Pearson correlation analysis.