Cofactor Independent Phosphoglycerate Mutase of Brugia malayi Induces a Mixed Th1/Th2 Type Immune Response and Inhibits Larval Development in the Host
Figure 5
Bm-iPGM specific IgG antibody and antibody isotypes. (a) Antibodies were detected by ELISA in the pooled sera of BALB/c mice administered with Bm-iPGM along with adjuvant and PBS only. Elevated IgG level was maintained in the Bm-iPGM immunized group. (b) Anti-Bm-iPGM antibody isotype levels (IgG1, IgG2a, IgG2b, IgG3, IgM, and IgA) in the pooled sera of Bm-iPGM immunized, adjuvant immunized, and control groups. Considerable increase in the levels of all the isotypes was noticed. Each bar represents mean of triplicate OD values taken at 492 nm each obtained with pooled sera of five experimental animals.
