Cofactor Independent Phosphoglycerate Mutase of Brugia malayi Induces a Mixed Th1/Th2 Type Immune Response and Inhibits Larval Development in the Host
Figure 7
In vitro lymphocyte proliferation. Proliferation was assessed in the splenocytes isolated from immunized, adjuvant, and control group of Mastomys by radioactive incorporation of -thymidine after stimulation with either concanavalin A (2.5 μg/mL) or Bm-iPGM (2.5 μg/mL). Radioactive incorporation in the cells was measured and results are expressed as stimulation index. (a) Batch A: euthanized on day 30 after larval challenge. (b) Batch B: euthanized on day 180 after larval challenge.
