Transforming Growth Factor-Beta (TGF-β) Signaling in Paravertebral Muscles in Juvenile and Adolescent Idiopathic Scoliosis

Figure 2

Evaluation of the transcriptional profile of TGF-βs and their receptors TGFBRs in paravertebral muscles of JIS group A and AIS group B by qRT-PCR. Box and whisker plots illustrating statistically significant (nonparametric Mann-Whitney test, ) results of the comparison of the mRNA abundance of TGF-βs and TGFBRs between concave and convex sides of the curve in both analyzed groups. AM1, AM2, respectively, paravertebral muscle of concave and convex side of the curve in JIS group and BM1, BM2 samples from concave and convex side of the curve in AIS group.