Transforming Growth Factor-Beta (TGF-β) Signaling in Paravertebral Muscles in Juvenile and Adolescent Idiopathic Scoliosis

Figure 3

TGF-β responsive genes in the paravertebral muscles of JIS and AIS patients. Matrix plot illustrating the degree of differentiation of 1050 mRNA IDs of TGF-β responsive genes between the transcriptomes of muscular tissue in dependence of the side of the curve (M1 versus M2) and the age of scoliosis onset (A versus B). Red spots upregulated genes, blue spots downregulated genes. M1, M2: respectively muscular tissue samples from curve concavity and convexity, A: juvenile idiopathic scoliosis; B: adolescent idiopathic scoliosis.