Table 4: GO analysis results of miR-15b regulated PIN. The common GO terms for miR-15b were listed.

MIMAT0000417 (Hsa-miR-15b)
GO termGenes value

GO:0006916~antiapoptosisBFAR, HSP90B1, GSK3B, BCL2, HIPK3, TGFBR1, NPM1, UBC, SERPINB2, FAIM3, BCL2L1, HSPA5

GO:0009891~positive regulation
of biosynthetic process
DVL3, HRAS, THRB, GRIP1, PCBD1, RXRB, RXRA, TGFBR1, PPARG, DDX5, CALR, POT1, SREBF2, ATXN1, MAPK1, MEIS2, PSMC5, NCOA2, HNF4A, ATXN7, NPM1, UBC, YAP1

GO:0010557~positive regulation
of macromolecule biosynthetic process
DVL3, HRAS, THRB, GRIP1, PCBD1, RXRB, RXRA, TGFBR1, PPARG, DDX5, CALR, POT1, SREBF2, ATXN1, MAPK1, MEIS2, PSMC5, NCOA2, HNF4A, ATXN7, UBC, YAP1

GO:0010604~positive regulation
of macromolecule metabolic process
HRAS, THRB, GRIP1, PPARG, PSMD1, PSMD2, PSMD3, H2AFX, PSMD4, YAP1, PSMD6, PSMD7, PRKCA, PCBD1, RXRB, RXRA, PSMA2, UBE2N, MAPK1, NCOA2, HNF4A, PSMA6, PSMA3, UBC, MDM2, CALR, POT1, PIN1, PSMB5, MEIS2, BCL2, UBE2D1, DVL3, TGFBR1, DDX5, FURIN, SREBF2, ATXN1, PSMC6, PSMD14, PSMD13, PSMC5, PSMD12, PSMC4, PSMC3, PSMD11, PSMD10, ATXN7, PSMC2, PSMC1

GO:0010605~negative regulation
of macromolecule metabolic process
THRB, TSG101, PPARG, BCL2L1, TERF2IP, CALR, POT1, PSMB5, MEIS2, NPM1, PSMD1, PSMD2, PSMD3, PSMD4, UBE2D1, PSMD6, PSMD7, PRKCA, RXRA, ZNF24, UBE2I, FURIN, CDK5, SIRT3, PSMA2, ATXN1, PSMD14, PSMC6, PSMD13, NCOA2, PSMC5, PSMA6, HNF4A, PSMD12, PSMC4, PSMC3, PSMD11, PSMD10, PSMC2, PSMA3, PSMC1, UBC, BUB1B, MDM2, FABP4, SMURF2

GO:0010628~positive regulation
of gene expression
DVL3, THRB, GRIP1, RXRB, PCBD1, RXRA, TGFBR1, PPARG, DDX5, SREBF2, ATXN1, MAPK1, MEIS2, PSMC5, NCOA2, HNF4A, ATXN7, UBC, YAP10.0031

GO:0010941~regulation of cell deathHRAS, BCAR1, BCL2L1, CALR, ITSN1, DYNLL1, BCL2, SOS1, CASP8, RAC1, NPM1, POU4F1, HSPA5, PRKCA, VAV3, TP53BP2, TGFBR1, TMBIM6, RXRA, ACTN1, ACTN2, FURIN, VAV1, CDK5, CASP10, MAPK1, BFAR, HSP90B1, PSMC5, GSK3B, HIPK3, UBC, SERPINB2, ERN1, FAIM3, MAPK8, CACNA1A

GO:0031328~positive regulation
of cellular biosynthetic process
DVL3, HRAS, THRB, GRIP1, PCBD1, RXRB, RXRA, TGFBR1, PPARG, DDX5, CALR, POT1, SREBF2, ATXN1, MAPK1, MEIS2, PSMC5, NCOA2, HNF4A, ATXN7, NPM1, UBC, YAP1

GO:0042981~regulation of apoptosisHRAS, BCAR1, BCL2L1, CALR, ITSN1, DYNLL1, BCL2, SOS1, CASP8, RAC1, NPM1, POU4F1, HSPA5, PRKCA, VAV3, TP53BP2, TGFBR1, TMBIM6, RXRA, ACTN1, ACTN2, FURIN, VAV1, CDK5, CASP10, MAPK1, BFAR, HSP90B1, GSK3B, HIPK3, UBC, SERPINB2, ERN1, FAIM3, MAPK8, CACNA1A

GO:0043066~negative regulation
of apoptosis
HRAS, TMBIM6, TGFBR1, BCL2L1, ITSN1, FURIN, BFAR, HSP90B1, GSK3B, HIPK3, BCL2, NPM1, UBC, SERPINB2, FAIM3, MAPK8, HSPA5, CACNA1A

GO:0043067~regulation
of programmed cell death
HRAS, BCAR1, BCL2L1, CALR, ITSN1, DYNLL1, BCL2, SOS1, CASP8, RAC1, NPM1, POU4F1, HSPA5, PRKCA, VAV3, TP53BP2, TGFBR1, TMBIM6, RXRA, ACTN1, ACTN2, FURIN, VAV1, CDK5, CASP10, MAPK1, BFAR, HSP90B1, PSMC5, GSK3B, HIPK3, UBC, SERPINB2, ERN1, FAIM3, MAPK8, CACNA1A

GO:0043069~negative regulation
of programmed cell death
HRAS, TMBIM6, TGFBR1, BCL2L1, ITSN1, FURIN, BFAR, HSP90B1, PSMC5, GSK3B, HIPK3, BCL2, NPM1, UBC, SERPINB2, FAIM3, MAPK8, HSPA5, CACNA1A

GO:0045941~positive regulation
of transcription
DVL3, THRB, GRIP1, RXRB, PCBD1, RXRA, TGFBR1, PPARG, DDX5, SREBF2, ATXN1, MAPK1, MEIS2, PSMC5, NCOA2, HNF4A, ATXN7, UBC, YAP10.0022

GO:0060548~negative regulation
of cell death
HRAS, TMBIM6, TGFBR1, BCL2L1, ITSN1, FURIN, BFAR, HSP90B1, PSMC5, GSK3B, HIPK3, BCL2, NPM1, UBC, SERPINB2, FAIM3, MAPK8, HSPA5, CACNA1A