Elevated Serum Vascular Cell Adhesion Molecule-1 Is Associated with Septic Encephalopathy in Adult Community-Onset Severe Sepsis Patients

Table 3

Laboratory data of the septic encephalopathy (SE) and non-SE groups in severe sepsis patients.

	SE group; 𝑛=23	Non-SE group; 𝑛=47	P value
WBC/DC (mean ± SD)
WBC (×10^9/L)	15.0±10.0	17.7±12.0	0.13
Segment (%)	76.7±20.3	81.8±17.3	0.38
Band (%)	8.5±12.7	3.2±4.8	0.06
Lymphocyte (%)	7.7±7.9	10.4±17.4	0.96
Biochemistry (mean ± SD)
Glucose (mg/dL)	210±162	171±94	0.91
Creatinine (mg/dL)	2.9±1.9	2.3±2.5	0.06
Lactate (mg/dL)	50.5±37.6	32.6±20.3	0.05*
Total bilirubin (mg/dL)	3.3±3.0	2.2±2.7	0.09
BNP (pg/mL)	991±1127	742±1024	0.21
Inflammatory markers (mean ± SD)
CRP (mg/L)	231±112	206±137	0.40
Procalcitonin (ng/mL)	32.5±33.4	35.6±59.4	0.12
sICAM-1Day1 (ng/mL)	1028.2±525.2	764.8±504.9	0.03*
sVCAM-1Day1 (ng/mL)	3048.1±1261.1	1969.0±1129.5	0.001*
sP-selectinDay1 (ng/mL)	98.8±42.5	98.0±23.0	0.77
sL-selectinDay1 (ng/mL)	1208.2±777.5	933.9±311.9	0.10
sE-selectinDay1 (ng/mL)	214.2±111.9	117.8±127.6	0.22

WBC: white blood cells; DC: differential count; CRP: C-reactive protein; BNP: B-type natriuretic peptide; sE-selectin: soluble E-selectin; sICAM-1: soluble intercellular adhesion molecule-1; sL-selectin: soluble L-selectin; sP-selectin: soluble P-selectin; sVCAM-1: soluble vascular cell adhesion molecule-1.
^∗𝑃<0.05.