Research Article

Propofol Protects the Immature Rabbit Heart against Ischemia and Reperfusion Injury: Impact on Functional Recovery and Histopathological Changes

Table 1

Changes in hemodynamic parameters.
(a) Changes in developed and end diastolic pressures

Developed pressure (mmHg)End diastolic pressure (mmHg)
Equilibrium End of protocolEquilibrium End of ischemiaEnd of protocol

Control
Propofol (g/mL)
 1
 2
 4
 10
Cyclosporine A

Data are presented as mean ± SE. *1 versus control and 10 μg/mL of propofol; *2 versus 10 g/mL of propofol.
(b) Changes in coronary flow following ischemia and reperfusion

Coronary flow (mL/min)Recovery (%)
Equilibrium End of protocol

Control
Propofol (g/mL)
 1
 2
 4
 10
Cyclosporine A

Data are presented as mean ± SE. versus control; a versus control.