Research Article
Propofol Protects the Immature Rabbit Heart against Ischemia and Reperfusion Injury: Impact on Functional Recovery and Histopathological Changes
Table 1
Changes in hemodynamic parameters.
(a) Changes in developed and end diastolic pressures |
| | Developed pressure (mmHg) | End diastolic pressure (mmHg) | | Equilibrium | End of protocol | Equilibrium | End of ischemia | End of protocol |
| Control | | | | | | Propofol (g/mL) | | | | | | 1 | | | | | | 2 | | | | | | 4 | | | | | | 10 | | | | | | Cyclosporine A | | | | | |
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Data are presented as mean ± SE. *1 versus control and 10 μg/mL of propofol; *2 versus 10 g/mL of propofol.
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(b) Changes in coronary flow following ischemia and reperfusion |
| | Coronary flow (mL/min) | Recovery (%) | | Equilibrium | End of protocol |
| Control | | | | Propofol (g/mL) | | | | 1 | | | | 2 | | | | 4 | | | | 10 | | | | Cyclosporine A | | | |
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Data are presented as mean ± SE. versus control; a versus control.
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