Fenugreek Seed Extract Inhibit Fat Accumulation and Ameliorates Dyslipidemia in High Fat Diet-Induced Obese Rats

Table 8

Effect of aqueous extract of Trigonella foenum-graecum (AqE-TFG) on serum lipase, lactate dehydrogenase (LDH), aspartate amino transferase (AST), and alanine amino transferase (ALT) levels in high fat diet- (HFD-) induced obese rats.

Groups	Lipase (U/L)	LDH (IU/L)	AST (IU/L)	ALT (IU/L)
Normal control	671.20±63.59	29.67±2.81	56.70±3.58	27.63±2.30
HFD control	1594.61±121.04^##	65.83±3.75^##	96.23±4.92^##	59.78±4.50^##
HFD + AqE-TFG (0.5 g/kg)	1237.13±102.53^∗	46.35±4.23^∗∗	75.52±5.62^∗∗	42.08±4.31^∗
HFD + AqE-TFG (1 g/kg)	1062.32±78.90^∗∗	38.22±2.55^∗∗	64.88±3.79^∗∗	36.45±3.12^∗∗
HFD + orlistat (10 mg/kg)	920.78±89.75^∗∗	34.06±4.44^∗∗	61.27±3.16^∗∗	33.64±5.16^∗∗

Results are expressed as mean ± S.E.M. (𝑛=10); ^##𝑃<0.01 compared to normal control; ^∗𝑃<0.05 and ^∗∗𝑃<0.01 compared to HFD control.