Subchondral Bone Plate Thickening Precedes Chondrocyte Apoptosis and Cartilage Degradation in Spontaneous Animal Models of Osteoarthritis
Figure 2
BMD of Sbp measured by a micro-CT scanner. DH () had a significantly denser medial Sbp than BS2 () at 16 weeks of age (unpaired -test, ). However, at 30 weeks, the opposite was observed in the lateral side of Sbp (unpaired -test, ). Over time, only the medial side of DH showed a dramatic increase of BMD between 10 and 16 weeks (one-way ANOVA followed by Bonferroni post hoc test, ). The data are expressed as mean ± SEM.
