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BioMed Research International
Volume 2014, Article ID 606870, 10 pages
http://dx.doi.org/10.1155/2014/606870
Research Article

Subchondral Bone Plate Thickening Precedes Chondrocyte Apoptosis and Cartilage Degradation in Spontaneous Animal Models of Osteoarthritis

1Centre for Comparative and Clinical Anatomy, University of Bristol, Southwell Street, Bristol BS2 8EJ, UK
2Imaging Laboratory, Department of Archaeology and Anthropology, University of Bristol, Bristol BS8 1UU, UK
3School of Veterinary Science, University of Bristol, Langford, Bristol BS40 5DU, UK
4School of Clinical Sciences, University of Bristol, Musculoskeletal Research Unit, Avon Orthopaedic Centre, Southmead Hospital, Bristol BS10 5NB, UK

Received 10 February 2014; Accepted 11 May 2014; Published 18 June 2014

Academic Editor: Rene C. Verdonk

Copyright © 2014 Zaitunnatakhin Zamli et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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