Mechanisms of Ascorbyl Radical Formation in Human Platelet-Rich Plasma
Effect of the COX inhibitor (a), LOX inhibitor (b), and CYP450 inhibitor (c) on formation in human PRP (approximately platelets/mL). The ESR spectra are labeled to show their components: DMPO- adduct (*). The ESR signal intensity rates and data in the bar chart are expressed as the means ± SEM (). , compared with the solvent control. The instrument parameters were identical to those shown in Figure 1(a).