The Role of Intrinsic Pathway in Apoptosis Activation and Progression in Peyronie’s Disease
Bax immunostaining in plaque from a patient with Peyronie’s disease (a, b, c) and in control tissue (d); magnification is 20x for all. Scale bar = 100 μm. Asterisk at (a): areas of osseous metaplasia with heterotopic ossification; double arrowhead: an osteocyte in bone lacunae; arrow: bax overexpression in an osteoblast of a primary ossification center. Arrow at (b): bax overexpression in an osteocyte in metaplastic bone; double arrowhead: bax overexpression in osteoblasts and fibroblasts on the border of the metaplastic bone tissue; asterisk: bax overexpression in a blood vessel.