Mannan-Binding Lectin in Cardiovascular Disease

Table 1

Major associations of mannan-binding lectin with myocardial infarction in humans.

Suggested MBL effect	Clinical association	Reference
Harmful	“High MBL” genotypes more frequent and higher levels of MBL in sera of patients with acute MI compared to controls	Pesonen et al. [72]
	Higher levels in patients with STEMI and LVEDF <35% comparing to controls with STEMI and LVEDF >35%	Haahr-Pedersen et al. [73]
	High serum levels associated with increased postinfarct ventricular ESV and EDV in STEMI patients	Schoos et al. [75]
	Low serum levels associated with lower mortality	Trendelenburg et al. [76]
Protective	High serum level associated with decreased risk of MI	Saevarsdottir et al. [80]
	“MBL deficient” genotypes connected with higher likelihood of MI at middle age	Vengen et al. [81]