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BioMed Research International
Volume 2014, Article ID 618382, 15 pages
Review Article

Tamponade or Filling Effect: Changes of Forces in Myopic Eyes

1Eye Clinic, Department of Neurological and Vision Sciences, University of Brescia, Piazzale Spedali Civili 1, 25123 Brescia, Italy
2Eye Clinic, Istituto Clinico Humanitas, Via Manzoni 56, 20089 Milano, Italy
3Eye Clinic, Department of Health Sciences, University of Molise, Via de Santis, 86100 Campobasso, Italy

Received 24 January 2014; Accepted 22 June 2014; Published 2 July 2014

Academic Editor: Xun Xu

Copyright © 2014 Francesco Semeraro et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Myopia is the most common ocular abnormality. Its high and growing prevalence has contributed to a recent surge in surgical interest in the disorder, since retinal detachment in eyes with high myopia differs from that in emmetropic eyes or eyes with low myopia. The myopic eye, because of its specific anatomy, poses special challenges that need to be overcome to ensure the appropriate use of vitreous substitutes. However, intraocular tamponades have shown great potential for revolutionizing retinal detachment surgery and vitreomacular surgery in general in myopic eyes. We provide an updated review of the clinical use of vitreous substitutes in the myopic eye, paying particular attention to analyzing the ideal function of endotamponade agents and comparing the effects of these agents on the physical and biological properties of the eye.