Large-Scale Investigation of Human TF-miRNA Relations Based on Coexpression Profiles

Table 1

Putative transcription factors regulating miR-122 gene. The bold items indicate the experimental-supported TFs. PCC represents the Pearson’s correlation coefficient between each TF-encoded gene and miR-122.

Matrix_ID	Transcription factor	Gene	PCC	Occurrence
V$ELF1_Q6	Elf-1	ELF1	0.192827	242
V$MAFB_01	MAFB	MAFB	0.383476	239
V$TBX5_02	TBX5	TBX5	0.132419	227
V$NR1B2_Q6	NR1B2	RARB	0.117271	226
V$CDX2_Q5_02	CDX-2	CDX2	0.105817	215
V$GATA1_01	GATA-1	GATA1	0.0128229	215
V$SMAD3_Q6_01	Smad3	SMAD3	0.0915205	203
V$HNF4A_Q6_01	HNF-4alpha	HNF4A	0.316168	191
V$SOX5_01	SOX5	SOX5	0.149287	185
V$SPI1_03	SPI1	SPI1	0.268782	178
V$ERBETA_Q5	ER-beta	ESR2	0.303769	176
V$GATA1_02	GATA-1	GATA1	0.0128229	173
V$GATA1_05	GATA-1	GATA1	0.0128229	168
V$GATA1_06	GATA-1	GATA1	0.0128229	168
V$CDX2_Q5_01	Cdx-2	CDX2	0.105817	167
V$MAZ_Q6	MAZ	MAZ	0.414832	166
V$MYOD_Q6_01	MyoD	MYOD1	0.306424	164
V$PITX3_Q2	PITX3	PITX3	0.127413	160
V$ING4_01	ING4	ING4	0.234372	158
V$HNF3B_Q6	HNF-3beta	FOXA2	0.44036	154
V$CDX2_01	Cdx-2	CDX2	0.105817	152
V$CRX_Q4	Crx	CRX	0.243011	149
V$HNF3A_01	HNF3A	FOXA1	0.140429	148
V$GATA1_04	GATA-1	GATA1	0.0128229	139
V$ERR1_Q3	ERR1	ESRRA	0.18197	135
V$CEBPE_Q6	CEBPE	CEBPE	0.0949125	133
V$HNF1_02	HNF-1alpha	HNF1A	0.363153	122
V$CRX_02	Crx	CRX	0.243011	119
V$NEUROD_02	NeuroD	NEUROD1	0.0402891	114
V$MAZ_Q6_01	MAZ	MAZ	0.414832	110
V$OC2_Q3	OC-2	ONECUT2	0.124899	102
V$IRF7_Q3	IRF-7	IRF7	0.13082	100
V$PIT1_Q6	Pit-1	POU1F1	0.319886	99
V$DBP_Q6_01	DBP	DBP	0.043001	76
V$CEBPG_Q6_01	C/EBPgamma	CEBPG	0.027117	73
V$MYOD_01	MyoD	MYOD1	0.306424	72
V$CREL_01	c-Rel	REL	0.29444	44
V$CEBPG_Q6	C/EBPgamma	CEBPG	0.027117	43
V$ATF4_Q6	ATF-4	ATF4	0.0251237	40
V$HOXA7_01	HOXA7	HOXA7	0.397453	31
V$E2F1_Q4	E2F-1	E2F1	0.110614	29
V$ATF5_01	ATF5	ATF5	0.912782	26