Factors Determining Disease Duration in Alzheimer’s Disease: A Postmortem Study of 103 Cases Using the Kaplan-Meier Estimator and Cox Regression

Table 1

Demographic details of the 103 cases used in the study (𝑁: number of cases; FAD: familial Alzheimer’s disease; SAD: sporadic Alzheimer’s disease). Data for age at death, duration, and disease onset are means with range and standard deviations in parentheses.

Patient group	𝑁	Age at death (years)	Duration (years)	Onset (years)
Early-onset FAD	19	61.9 (46–74, 10.8)	11.1 (3–20, 6.5)	50.7 (38–59, 6.5)
Early-onset SAD	22	70.4 (57–88, 11.1)	16.0 (6–30, 9.3)	54.4 (49–58, 4.2)
Late-onset FAD	12	77.4 (70–85, 5.1)	7.0 (1–15, 4.6)	70.4 (61–84, 7.6)
Late-onset SAD	50	80.1 (70–98, 6.6)	6.8 (1–21, 4.5)	73.5 (62–93, 7.2)