The Chromosome 9p21 Variant Not Predicting Long-Term Cardiovascular Mortality in Chinese with Established Coronary Artery Disease: An Eleven-Year Follow-Up Study
Table 1
The clinical characteristics and genotypic frequency of study subjects at baseline.
CAD ()
Non-CAD ()
Age (year)
67.6 ± 10.0
64.5 ± 10.8
<0.001
Male, (%)
742 (80.2%)
408 (64.4%)
<0.001
BMI (kg/m2)
25.3 ± 3.3
25.3 ± 3.5
0.954
Systolic BP (mmHg)
126 ± 13
126 ± 11
0.490
Diastolic BP (mmHg)
71 ± 10
71 ± 11
0.813
Current smoking, (%)
260 (28.1%)
128 (20.2%)
<0.001
Hypertension, (%)
466 (50.4%)
280 (44.2%)
0.032
Diabetes mellitus, (%)
344 (37.2%)
137 (21.6%)
<0.001
Triglyceride (mmol/L)
1.6 ± 1.3
1.5 ± 1.4
0.045
Total cholesterol (mmol/L)
4.8 ± 1.2
4.4 ± 1.2
<0.001
HDL cholesterol (mmol/L)
1.1 ± 0.3
1.2 ± 0.4
0.312
LDL cholesterol (mmol/L)
2.9 ± 1.0
2.6 ± 0.9
<0.001
Fasting glucose (mmol/L)
6.8 ± 2.7
6.1 ± 2.1
<0.001
Genotype (rs4977574)
0.002
AA
198 (21.4%)
181 (28.5%)
AG
479 (51.8%)
318 (50.2%)
GG
248 (26.8%)
135 (21.3%)
Allele (rs4977574)
A
875 (47.3%)
680 (53.6%)
G
975 (52.7%)
588 (46.4%)
BMI: body mass index, BP: blood pressure, HDL: high-density lipoprotein, and LDL: low-density lipoprotein.
