Research Article

Can Ki-67 Play a Role in Prediction of Breast Cancer Patients' Response to Neoadjuvant Chemotherapy?

Table 3

Therapeutical aspects as a function of Ki-67.

ParameterKi-67 ≤15% Ki-67 16–50%Ki-67 >50%

Number of patients 223718
Initial sonographic tumor diameter (mm)29.3 ± 14.032.2 ± 15.0 31.1 ± 10.40.738
Postoperative histologic tumor diameter (mm)14.6 ± 9.918.6 ± 21.711.0 ± 15.30.312
Change (% from initial tumor size)57.9 ± 44.952.0 ± 66.239.4 ± 50.70.590
Sonographic change (% from initial tumor size)47.6 ± 22.238.2 ± 32.834.4 ± 37.00.373
Grade of regression (Sinn)1.7 ± 1.12.2 ± 1.22.1 ± 1.40.310
Number of patients with pCR4 (18.1%)10 (27%)6 (33.3%)