Low Perceived Social Support Is Associated with CD8+CD57+ Lymphocyte Expansion and Increased TNF-α Levels
Table 2
Immune and cortisol values in the MSPSS groups according to low (<65.0) and high (≥65.0) MPSS score. Results are expressed as median (25th–75th percentile).
Low MSPSS score
High MSPSS score
Lymphocyte subpopulation
Total Lymphocytes (cells/mm3)
2164 (1778–2644)
2298 (1915–2661)
CD19+ lymphocytes (cells/mm3)
269 (185–358)
269 (193–351)
CD3+CD4+ lymphocytes (cells/mm3)
1077 (866–1273)
1159 (897–1425)
CD8+ lymphocytes (cells/mm3)
558 (443–795)
596 (490–686)
CD8+CD57+ lymphocytes (cells/mm3)
163 (95–222)
110 (73–173)*
CD3−CD56+CD16+ lymphocytes (cells/mm3)
215 (164–300)
201 (137–283)
Cytokines
IL-1 (pg/mL)
0.6 (0.2–2)
0.7 (0.2–1.7)
IL-6 (pg/mL)
1.3 (0.7–4.3)
1.5 (0.9–4.2)
TNF- (pg/mL)
22.6 (7.5–46.1)
12.8 (6.0–23.4)*
INF- (pg/mL)
2.6 (1.6–3.9)
2.7 (1.3–3.8)
high versus low MSPSS score (Bonferroni-corrected Mann-Whitney test).
