Impact of the Prolymphangiogenic Crosstalk in the Tumor Microenvironment on Lymphatic Cancer Metastasis

Figure 1

The prolymphangiogenic crosstalk of the tumor microenvironment: tumor cells as well as macrophages, dendritic cells, the extracellular matrix, cancer-associated fibroblasts, and mesenchymal stem cells can promote lymphangiogenesis by secretion or expression of different factors.