Mas-Mediated Antioxidant Effects Restore the Functionality of Angiotensin Converting Enzyme 2-Angiotensin-(1–7)-Mas Axis in Diabetic Rat Carotid
Figure 3
Concentration-response curves for angiotensin II or angiotensin-(1–7) in endothelium-intact (E+) carotid from control or diabetic rats after the in vitro pretreatment with losartan or DCPIB. Effect of the in vitro pretreatment with losartan or DCPIB on the relaxation induced by angiotensin II (a) or angiotensin-(1–7) (b). Angiotensin II (c) or angiotensin-(1–7) (d) before or after the in vitro pretreatment with losartan or DCPIB. The values are significantly different (; ) from nonpretreated carotid rings (E+) from nontreated control () or diabetic (#) rats.
