Morphohistological Features of Pancreatic Stump Are the Main Determinant of Pancreatic Fistula after Pancreatoduodenectomy

Table 1

Fibrosis and inflammation grading at histology and final score computation.

Pancreatic stump fibrosis-and-inflammation score
Grade of fibrosis	Score	Grade of inflammation	Score
No fibrosis	0	No inflammation	0
Local Fibrosis (lobular or acinar)	1	Focal inflammation	1
Lobular generalized fibrosis	2	Generalized inflammation	2
Acinar generalized fibrosis	3
Subtotal fibrosis	4
Final score computation
0–2	Regular pancreas or mild alterations: perilobular or periacinar fibrosis, no inflammation or focal inflammation
3-4	Moderate tissue alterations: perilobular generalized fibrosis, focal or diffuse inflammatory infiltrate
5-6	Generalized fibrosis with total or subtotal disruption of acinar structure, intense inflammation