Chondroitin Sulfate Proteoglycans: Structure-Function Relationship with Implication in Neural Development and Brain Disorders
Figure 3
(a) Representation of the favorable (white polygons) and unfavorable (grey polygons) hydrophobic areas of risperidone (biological activity on D2 = 8.18) when its antagonist potency at dopamine D2 receptor is considered and (b) representation of the favorable (white polyhedral) and unfavorable (grey polyhedral) hydrophobic areas of risperidone (biological activity on 5HT2A = 9.76) when its antagonist potency at the serotonin 5HT2A receptor is considered [after Avram et al. [77], copyright permission].
