Azadirachta indica Attenuates Cisplatin-Induced Nephrotoxicity and Oxidative Stress

Table 3

Protective effects of methanolic leaves extract of neem on cisplatin-induced alternation in enzymatic antioxidant molecules of rats.

Groups	GR; (μmol/hr/mg protein)	GST; (μmol/hr/mg protein)	GPx; (U/mg protein)
Con	12.43±1.05	0.07±0.003	64.37±3.36
CP	6.31±0.78^a	0.02±0.003^a	35.19±2.03^a
N-CP	15.76±1.36^ab	0.07±0.003^b	61.70±4.87^b
CP-N	22.10±1.53^ab	0.09±0.004^ab	75.49±5.11^ab

Values are mean ± SEM (𝑛=7).
^a𝑃<0.05, significant change with respect to control; ^b𝑃<0.05, significant change with respect to CP for Duncan’s post hoc test.