In Vitro and In Vivo Effects of Suppressor of Cytokine Signalling 7 Knockdown in Breast Cancer: The Influence on Cellular Response to Hepatocyte Growth Factor

Figure 6

(a) A representative ECIS wounding experiment to study in vitro migration rate of MDA-MB-231. ECIS time course following electrical wounding (6V for 30 Sec). Wells: (1) MDA-MB-231^ΔSOCS (untreated); (2) MDA-MB-231^ΔSOCS7 (+HGF/U73122); (3) MDA-MB-231^ΔSOCS7 (+HGF); (4) MDA-MB-231^pEF6 (+HGF/U73122); (5) MDA-MB-231^pEF6 (+HGF); and (6) MDA-MB-231^WT (untreated). (b) In vitro migration of MDA-MB-231 sublines with and without HGF.

(a)

(b)