In Vitro and In Vivo Effects of Suppressor of Cytokine Signalling 7 Knockdown in Breast Cancer: The Influence on Cellular Response to Hepatocyte Growth Factor

Table 5

The in vitro migration of MCF7 as measured by relative wound area (%). Values represent Mean (SD).

Cell lines		MCF7^ΔSOCS7		𝑃
	Incubation medium	HGF
MCF7^pEF6	HGF	31.9  (19.6)  vs. 54.7 (15.5)		0.019
Cell lines		MCF7^pEF6	MCF7^ΔSOCS7	𝑃
		HGF
MCF7^pEF6	Serum free only	54.7  (15.5)  vs. 73.4 (9.8)		0.028
MCF7^ΔSOCS7			31.9  (19.6)  vs. 50.6 (5.9)	0.045
		Pretreatment with U73122 then HGF
MCF7^pEF6	HGF	55.9  (17.2)  vs. 54.7 (15.5)		0.9
MCF7^ΔSOCS7			59.8  (20.3)  vs. 31.9 (19.6)	0.005