In Vitro and In Vivo Effects of Suppressor of Cytokine Signalling 7 Knockdown in Breast Cancer: The Influence on Cellular Response to Hepatocyte Growth Factor

Table 6

The in vitro migration of MDA-MB-231 as measured by relative wound area (%). Values represent mean (SD).

Cell lines		MDA^ΔSOCS7		𝑃
	Incubation medium	HGF
MDA^pEF6	HGF	34.9  (3.8)  vs. 58.5 (2)		0.01
Cell lines		MDA^pEF6	MDA^ΔSOCS7	𝑃
		HGF
MDA^pEF6	Serum free only	58.5  (2)  vs. 80.2 (4.5)		0.017
MDA^ΔSOCS7			34.9  (3.8)  vs. 54.3 (8)	0.017
		Pretreatment with U73122 then HGF
MDA^pEF6	HGF	71.8  (4)  vs. 58.5 (2)		0.87
MDA^ΔSOCS7			61.2  (16.2)  vs. 34.9 (3.8)	0.007