In Vitro and In Vivo Effects of Suppressor of Cytokine Signalling 7 Knockdown in Breast Cancer: The Influence on Cellular Response to Hepatocyte Growth Factor

Table 8

The in vitro migration rate of MDA-MB-231 (𝜇m/hr). Values represent Mean (SD).

Cell lines		MDA^ΔSOCS7		𝑃
	Incubation medium	HGF
MDA^pEF6	HGF	222  (48.1)  vs. 104.2 (36.1)		<0.001
Cell lines		MDA^pEF6	MDA^ΔSOCS7	𝑃
		HGF
MDA^pEF6	Serum free only	104.2  (36.1)  vs. 37.1 (2.6)		0.008
MDA^ΔSOCS7			222  (48.1)  vs. 138.9 (13.9)	<0.001
		Pretreatment with U73122 then HGF
MDA^pEF6	HGF	54.2  (10.2)  vs. 104.2 (36.1)		0.046
MDA^ΔSOCS7			59.3  (58.8)  vs. 222 (48.1)	<0.001