(a) Target sequence =
(b) Target sequence =
(c) Target sequence =
(d) Target sequence =
Figure 3: Average fitness score for 5000 generations of deselection (generation 201 to 5200). Panels (a), (b), (c), and (d) show 4 different resistant complexities (referred to as “target sequence”), respectively. The average population fitness and the average fitness of the fittest organism of each triplicated simulation are shown for each generation. For each target sequence, the corresponding average fitness scores at each generation for control (from Figure 2) are added for comparison. Hence, the average fitness scores for controls in each panel are identical. Paired -tests are performed between average population fitness and control for both TS and FPS.