PPI Network Analysis of mRNA Expression Profile of Ezrin Knockdown in Esophageal Squamous Cell Carcinoma
Figure 1
PPI subnetworks were constructed by mapping DEGs to HPRD PPI network. ((a)–(c)) PPI subnetworks for downregulated, upregulated, and total DEG, respectively. (d) EZR-central PPI subnetwork. (e) Internal interactions between DEGs. Square nodes represented proteins encoded by downregulated genes, while round nodes represented proteins encoded by upregulated genes. The other interacting proteins without significantly differentially expression were represented as diamond-shaped nodes.
