Phenotypic Switch Induced by Simulated Microgravity on MDA-MB-231 Breast Cancer Cells

Table 1

	Roundness	±SE		Solidity	±SE		FD	±SE
24 hours
On ground cells	0,4563	0,0301		0,6690	0,0225		1,7482	0,0091
RPM adherent cells	0,3991	0,0275		0,6499	0,0200		1,7406	0,0063
RPM cell clumps	0,7894	0,0219	**	0,8966	0,0263	**	1,4625	0,0015	**
72 hours
On ground cells	0,3227	0,0263		0,4687	0,0136		1,6677	0,0036
RPM adherent cells	0,4081	0,0311		0,6115	0,0226	*	1,7245	0,0067
RPM cell clumps	0,7961	0,0208	**	0,8573	0,0469	**	1,4990	0,0015	**

Roundness, solidity, and fractal dimension (FD) mean values ± SE in on ground control cells, RPM adherent cells, and RPM cell clumps. *P < 0.01 versus on ground control cells; **P < 0.001 versus on ground control and RPM adherent cells by ANOVA followed by Bonferroni post-test.