The Role of Bioactive Lipids in Stem Cell Mobilization and Homing: Novel Therapeutics for Myocardial Ischemia

Figure 5

Proposed BM-derived stem cell differentiation scheme in the presence of S1P. We propose that following myocardial infarction the role of S1P is twofold: mobilization of BMSPCs from their BM niches as well as promoting their subsequent differentiation into myocardial and endothelial lineages, thereby further aiding in myocardial repair following ischemic injury.